产品货号：
Z11081
中文名称：
Apolipoprotein AI/APOA1抗体
英文名称：
Anti-Apolipoprotein AI/APOA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Apolipoprotein AI/APOA1 Antibody |
| 指标别名 | Apo AI;ApoA I;APOA1;apolipoprotein A I;Apolipoprotein A1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM,ELISA |
| 基因名称 | APOA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human APOA1 recombinant protein (Position:D25-Q267).Human APOA1 shares 64% and 61.7% amino acid (aa) sequence identity with mouse and rat APOA1,respectively. |
| 实际分子量 | 24KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Apolipoprotein A-1,also known as APOA1,is a human protein with a specific role in lipid metabolism.It binds to lipopolysaccharide or endotoxin,and has a major role in the anti-endotoxin function of HDL.The gene is mapped to 11q23.And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence.The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion.It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters.ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor,and thus may have an anticlotting effect.Defects in the gene encoding it are associated with HDL deficiencies,including Tangier disease,and with systemic non-neuropathic amyloidosis.Additionally,ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport. |
| Uniprot ID | P02647 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | apolipoprotein A-I |
| 蛋白名全称 | Apolipoprotein A-I |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunohistochemistry(Frozen Section) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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